At least five people are dead and five others remain hospitalized after an Amazon Prime Air cargo plane overran the runway at Miami International Airport (MIA) on Sunday afternoon, plowing through an airport perimeter road and striking multiple civilian vehicles.
The aircraft, a 32-year-old Boeing 767-300 operated by charter carrier 21 Air, was arriving as Flight 7598 from San Juan, Puerto Rico, when it overshot Runway 30 just before 2:00 PM ET.
Miami-Dade Fire Rescue Chief Raied Jadallah confirmed that first responders faced an intense rescue operation on the perimeter road. Several victims were trapped inside mangled civilian vehicles struck by the incoming Boeing 767 and had to be cut free by emergency crews.
Three of the survivors sustained severe, life-threatening injuries and were rushed directly to the Ryder Trauma Center at Jackson Memorial Hospital. Medical teams continue to monitor them closely.
Two additional individuals were transported to local area hospitals with less severe injuries. They are currently reported to be in stable condition.
Officials confirmed five people died at the scene. Investigators are working to confirm whether the deceased were occupants of the struck vehicles or crew members on board the aircraft.
Over 200 firefighters responded to extinguish heavy flames and smoke. While the fire is out, teams are still mitigating a large aviation fuel leak. The nose and fuselage sustained extreme damage, with the plane resting nose-down in a field and roadway servicing an Amazon warehouse.
The disaster triggered an immediate ground stop on Sunday. While two of MIA's four runways have since reopened, the diagonal runway remains completely blocked by wreckage. Thousands of passengers face severe flight delays and cancellations during peak Labor Day weekend traffic. Nearby hubs like Fort Lauderdale (FLL) and Orlando (MCO) are actively managing diverted flights.
The National Transportation Safety Board (NTSB) and Federal Aviation Administration (FAA) have assumed control of the crash site. An NTSB "Go Team" is on-scene analyzing flight telemetry data, structural failure points—such as the plane's collapsed landing gear—and weather factors like crosswinds.
Both Amazon and 21 Air expressed profound grief over the tragedy, with Amazon's Director of Global Media Relations Kelly Nantel and 21 Air CEO Keith Winters confirming full cooperation with local authorities and federal investigators.